COSMIN database

Quality of life instruments and definitions in individuals with spinal cord injury: a systematic review

Hill, M. R., Noonan, V. K., Sakakibara, B. M., Miller, W. C., and Team, Scire Research
STUDY DESIGN: A systematic review.

OBJECTIVE: To critically review quality of life (QOL) instruments used with spinal cord injury (SCI) populations.

SETTING: Vancouver, Canada.

METHODS: A systematic literature review was conducted for publications assessing the measurement properties of QOL outcome measures. Pre-established criteria were used to evaluate the measurement properties.

RESULTS: Fourteen articles reporting on 13 QOL instruments met the inclusion criteria, including the Patient Reported Impact of Spasticity Measure (PRISM), Quality of Well-being Scale, Qualiveen, Sickness Impact Profile (SIP68), Short Form (SF)-36, SF-36V, SF-12, SF-6D, Quality of Life Index, Quality of Life Profile for Adults with Physical Disabilities (QOLP-PD), Satisfaction with Life Scale, Sense of Well-being Index (SWBI), and the World Health Organization Quality of Life-BREF scale (WHOQOL-BREF). The SF-36 and WHOQOL-BREF have been widely used and validated. The SIP68, QOLP-PD, SF-36V, and SWBI are promising with limited investigation. The Qualiveen and PRISM performed well and are specific to SCI complications.

CONCLUSION: The WHOQOL-BREF is presently the most acceptable and established instrument to assess QOL after SCI. The SIP68, QOLP-PD, SF-36V, and SWBI are promising; however, require further evaluation of their measurement properties.
Spinal Cord
1476-5624 (Electronic)
Publication year:
Symptom status:
Cognitive/mental state
Emotional state
Physical state
Functional status:
Physical functioning
Role functioning
Social functioning
General health perceptions / HRQoL:
Health-related quality of life
Adults (18-65)
Seniors (65+)
Injury, poisoning and certain other consequences of external causes
PRO / non-PRO:
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
2 - Interviews
PRISM - Patient Reported Impact of Spasticity Measure
QOLI - Quality of Life Index
QOLP-PD - Quality of Life Profile-Physical Disabilities
QWB - Quality of Well-Being Scale
SF-12 - 12-item Short Form Health Survey [alias: RAND-12]
SF-36 - 36-item Short Form Health Survey [alias: RAND-36][alias: Medical Outcomes Study (MOS) SF-36]]    |  | also see:
SF-36-V - 36-item Short Form Health Survey-Vitality subscale
SF-6D - Short-Form 6D (derived from SF-36 or F-12)
SIP-68 - Sickness Impact Profile 68
SWBI - Sense of Well-Being Index
SWLS - Satisfaction With Life Scale
WHOQOL-BREF - World Health Organization Quality of Life questionnaire–Abbreviated Questionnaire (versions: WHOQOL-HIV-BREF)