COSMIN database

Quality of life instruments in studies of chronic pelvic pain: a systematic review

Neelakantan, D., Omojole, F., Clark, T. J., Gupta, J. K., and Khan, K. S.
The use of quality of life (QoL) instruments in chronic pelvic pain (CPP) will allow a more objective assessment of patient-centred clinical outcomes. However, there is concern that not enough emphasis is placed on clinical face validity (i.e. issues which are of importance to patients and reflect their experiences and concerns). To explore this issue, we performed a systematic review of published research. Relevant papers were identified through electronic scanning of six electronic databases and by manual searching of bibliographies of known primary and review articles. Studies were selected if they assessed women with CPP for life quality, either developing QoL instruments or applying them as an outcome measure. Selected studies were assessed for the quality of their QoL instruments using a 17-item checklist, including 10 items for clinical face validity and seven items for measurement (psychometric) properties. A total of 19 articles were eligible for inclusion in the review. The generic Short Form 36 Health Survey Questionnaire (SF-36) was used most frequently, being employed in 10/19 (53%) of the studies. Three studies developed disease-specific QoL instruments for CPP complying with 59 - 77% of the quality criteria. Overall, quality assessment showed that only 4/18 (22.2%) studies complied with more than half the criteria for face validity, whereas 12/18 (66.6%) studies complied with more than half of the criteria for measurement properties (P = 0.0001). Among existing QoL instruments, compliance with the quality criteria for measurement properties is higher than for clinical face validity. There is a need to develop disease specific QoL instruments for CPP with face validity in addition to sound measurement properties.
J Obstet Gynaecol
0144-3615 (Print)
Publication year:
General health perceptions / HRQoL:
Health-related quality of life
Overall quality of life:
Overall quality of life
Adults (18-65)
Seniors (65+)
Diseases of and symptoms related to the genitourinary system
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
PRO / non-PRO:
Non-patient Reported Outcome
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
2 - Interviews
6 - Clinical rating scales
Activity Index
BDI - Beck Depression Inventory   
CES-D - Centre for Epidemiologic Studies-Depression Scale   
CPP/endometriosis QoL Questionnaire
Demand Control Questionnaire
EHP 30 - Endometriosis Health Profile 30 Questionnaire
Endometriosis Specific Questionnaire
EQ-5D - EuroQoL-5 Dimensions   
Euro QoL Evaluation - Euro Quality of Life Evaluation
FPQOLI - Ferrans and Powers Quality of Life Index
General Health Index
GHQ - General Health Questionnaire
Global QoL Questionnaire
HAM-D - Hamilton Rating Scale for Depression [alias: HDRS][alias: HRSD]   
Mental Health Index
NHP - Nottingham Health Profile   
Patient related index
POMS - Profile of Mood States
PSE - Present State Exam
Psychological Questionnaire
SAQ - Sexual Activity Questionnaire
SDS - Zung Self-rating Depression Scale
Sexual Health Questionnaire
SF-12 - 12-item Short Form Health Survey [alias: RAND-12]
SF-36 - 36-item Short Form Health Survey [alias: RAND-36][alias: Medical Outcomes Study (MOS) SF-36]]    |  | also see:
Sleep Quality Questionnaire
Social support in life
Wisconsin BPS - Wisconsin Brief Pain Scale/Questionnaire