COSMIN database

A systematic review of patient-reported outcome measures in head and neck cancer surgery

Pusic, A., Liu, J. C., Chen, C. M., Cano, S., Davidge, K., Klassen, A., Branski, R., Patel, S., Kraus, D., and Cordeiro, P. G.
OBJECTIVE: To identify, summarize, and evaluate patient-reported outcome questionnaires for use in head and neck cancer surgery with the view to making recommendations for future research.

DATA SOURCES: A systematic review of the English-language literature, with the use of head-and-neck-surgery-specific keywords, was performed in the following databases: Medline, Embase, HAPI, CINAHL, Science/Social Sciences Citation Index, and PsycINFO from 1966 to March 2006.

DATA EXTRACTION AND STUDY SELECTION: All English-language instruments identified as patient-reported outcome questionnaires that measure quality of life and/or satisfaction that had undergone development and validation in a head and neck cancer surgery population were included.

DATA SYNTHESIS: Twelve patient-reported outcome questionnaires fulfilled our inclusion criteria. Of these, four were developed from expert opinion alone or did not have a published development process and seven questionnaires lacked formal item reduction. Only three questionnaires (EORTC Head and Neck Module, University of Michigan Head and Neck Quality-of-life Questionnaire, and Head and Neck Cancer Inventory) fulfilled guidelines for instrument development and evaluation as outlined by the Medical Outcomes Trust.

CONCLUSIONS: Rigorous instrument development is important for creating valid, reliable, and responsive disease-specific questionnaires. As a direction for future instrument development, an increased focus on qualitative research to ensure patient input may help to better conceptualize and operationalize the variables most relevant to head and neck cancer surgery patients. In addition, the use of alternative methods of psychometric data analysis, such as Rasch, may improve the value of health measurement in clinical practice for individual patients.
Otolaryngol Head Neck Surg
0194-5998 (Print)
Publication year:
General health perceptions / HRQoL:
Health-related quality of life
Overall quality of life:
Overall quality of life
Adults (18-65)
Seniors (65+)
Diseases of and symptoms related to the musculoskeletal system and connective tissue
Neoplasms and related symptoms
PRO / non-PRO:
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
AQLQ - Auckland Quality-of-life Questionnaire
DSHNC - Disfigurement Scale for Head and Neck Cancer
EORTC QLQ-H&N35 - European Organization for Research and Treatment of Cancer Quality of Life Questionnaires Head & Neck 35
FACT-H&N - Functional Assessment of Cancer Therapy-Head and Neck
FSS-SR - Functional Status Scale Self Report
HNCI - Head and Neck Cancer Inventory
HNQOL - University of Michigan Head and Neck Quality of Life Questionnaire
H&NS - Head and Neck Survey
LASA - Linear Analogue Self-Assessment Questionnaire
MDADI - MD Anderson Dysphagia Inventory
NDII - Neck Dissection Impairment Index
UWQOL (Also: UWQOL-V4)- University of Washington Quality-of-life Instrument (also version 4)