COSMIN database

Measurement of oral mucositis in children: a review of the literature

Tomlinson, D., Judd, P., Hendershot, E., Maloney, A. M., and Sung, L.
GOALS OF WORK: The assessment of oral mucositis is important. There is a paucity of validated oral mucositis assessment instruments for use in children. This paper reviews the available mucositis measurement tools and their applicability to a paediatric population.

MATERIALS AND METHODS: Literature search of PUBMED and bibliography searches identified articles relevant to mucositis measurement tools and the measurement of mucositis in paediatrics.

RESULTS: The relevant issues in the literature could be grouped into three categories: (1) development and evaluation of oral assessment tools, (2) oral assessment in the paediatric population, and (3) challenges to the assessment of oral mucositis in children. There were numerous validated mucositis assessment scales for use in adults. Only three of these scales have received limited evaluation for use in the paediatric population. The unique challenges presented by the paediatric population are excluded from much of the discussion in the literature.

CONCLUSION: The paper demonstrates the need to consider the issues specific to children. It must be determined whether previously developed tools are ideally suited for children enrolled on mucositis clinical trials.
Support Care Cancer
0941-4355 (Print)
Publication year:
Symptom status:
Physical state
Children (0-18)
Codes for special purposes
Diseases of and symptoms related to the digestive system
Diseases of and symptoms related to the respiratory system
Neoplasms and related symptoms
PRO / non-PRO:
Non-patient Reported Outcome
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
6 - Clinical rating scales
7 - Observations
9 - Laboratory tests
Daily Mucositis Scale
DIM - Daily Index of Mucositis
MacDibbs Mouth Assessment
NCI-CTC - National Cancer Institute - Common Toxicity Criteria
OAG - Oral Assessment Guide (versions: ROAG - Revised OAG)
OMAS - Oral Mucositis Index Assessment Scale
OMI - Oral Mucositis Index
Oral Exam Guide
Oral Mucositis Daily Questionnaire
RTOG - Radiation Therapy Oncology Group
Spijkervet Radiation Mucositis
TS - Tardieu Scale (versions: MTS - Modified TS)
Walsh Scale
WCCNR - Western Consortium for Cancer Nursing Research
WHO - World Health Organization Grading System