COSMIN database

Patient-reported outcomes (PRO's) in glaucoma: a systematic review

Authors:
Vandenbroeck, S., De Geest, S., Zeyen, T., Stalmans, I., and Dobbels, F.
Abstract:
The aim of this review was to summarize literature in view of patient-reported outcome (PRO) instruments for glaucoma and provide guidance on how outcomes are best assessed based on evidence about their content and validity. A systematic literature review was performed on papers describing the developmental process and/or psychometric properties of glaucoma or vision-specific PRO-instruments. Each of them was assessed on their adherence to a framework of quality criteria. Fifty-three articles were identified addressing 27 PRO-instruments. In all, 18 PRO's were developed for glaucoma and 9 for diverse ophthalmologic conditions. Seven instruments addressed functional status, 11 instruments quality of life and 9 instruments disease and treatment-related factors. Most of the instruments demonstrated only partially adherence to predefined quality standards. The tools for assessing functional status were of poor quality, while the Glaucoma Quality of Life Questionnaire and the Vision Quality of Life Index were well-developed QoL measures, yet only validated using classical techniques. The Rasch-scaled QoL-tools, IVI and VCM1 need to improve their item-content for glaucoma patients. The questionnaires to measure adherence should improve their validity and the Treatment Satisfaction Survey for Intra Ocular Pressure pops out as the highest quality tool for measuring topical treatment side effects. This review revealed that most PRO-instruments demonstrated poor developmental quality, more specifically a lack of conceptual framework and item generation strategies not involving the patients' perspective. Psychometric characteristics were mostly tested using classical validation techniques.
DOI:
10.1038/eye.2011.45
URL:
https://www.ncbi.nlm.nih.gov/pubmed/21423144
Journal:
Eye (Lond)
issn:
1476-5454 (Electronic)
Publication year:
2011
pages:
555-77
Symptom status:
Physical state
Functional status:
Physical functioning
General health perceptions / HRQoL:
Health-related quality of life
Overall quality of life:
Overall quality of life
Age:
Adults (18-65)
Children (0-18)
Seniors (65+)
Disease:
Diseases of and symptoms related to the eye and adnexa
PRO / non-PRO:
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
2 - Interviews
Instrument:
Adherence questionnaire
COMTOL - Comparison of Ophthalmic Medication for Tolerability
EDSQ - Eye Drop Satisfaction Questionnaire
GHPI - Glaucoma Health Perceptions Index
Glaucoma self-efficacy scale
Glaucoma symptom identifier
Glaucoma utility index
Glausat
GQL-15 (Also GQL-36 or GLAU-QOL36) - Glaucoma Quality of Life-15 (Glaucoma Quality of Life-36)
GSS - Glaucoma Symptom Scale
Independent mobility questionnaire
IVI - Impact of Vision Impairment
LVQOL - Low Vision Quality Of Life questionnaire
NEI VFQ-19 - National eye institute visual function index-19 items
NEI VFQ-51 - National eye institute visual function index-51 items
Nursing home vision quality of life questionnaire
Outcome expectations scale
QoL-VFQ - Quality of life and visual function questionnaire
Questionnaire of Mills and Drance
Questionnaire of Ross et al
SIG - Symptom Impact Glaucoma Score
TSS-IOP - Treatment Satisfaction Survey-Intraocular Pressure
VAQ - Visual Activities Questionnaire
Vision core module 1
Vision quality of life index
Viswanathan et al. instrument