COSMIN database

Quality-of-life assessment in acute, chronic, and cancer pain: a pharmacist's guide

Bonomi, A. E., Shikiar, R., and Legro, M. W.
OBJECTIVE: To describe instrumentation, or measures, available for use in assessing the impact of pain on the quality of life (QOL) of patients, and methods to evaluate the appropriateness of these QOL measures.

DATA SOURCES: MEDLINE, PSYCHLit, and CANCERLit were searched from 1980 through 1997 to identify QOL instruments that included a pain subscale or pain-related items.

DATA SYNTHESIS: Given the high prevalence of chronic diseases or conditions that include pain as a primary or secondary symptom, pharmacists should understand how pain affects the QOL of patients. Over the past two decades, emphasis has increased on developing instruments that assess health-related QOL concerns, including pain. Scores of measures--including utility measures--are available to measure general QOL in patients with conditions involving pain. Condition-specific instruments have also been developed to measure the impact of specific conditions, such as arthritis, on QOL. Guidelines are presented for evaluating QOL instrumentation, and existing measures used to evaluate the QOL of patients with acute and chronic pain are described. Pharmacists can use these guidelines to evaluate the usefulness of existing instruments for assessing the QOL of patients with pain.

CONCLUSION: Using QOL measures in everyday practice may assist pharmacists in gaining insight into the effects of pain on their patients' QOL. This information may be useful in developing treatment programs that minimize pain and its associated side effects while maximizing patients' well-being.
J Am Pharm Assoc (Wash)
1086-5802 (Print)
Publication year:
Overall quality of life:
Overall quality of life
Adults (18-65)
Seniors (65+)
Codes for special purposes
Diseases of and symptoms related to the musculoskeletal system and connective tissue
Factors influencing health status and contact with health services
Neoplasms and related symptoms
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
PRO / non-PRO:
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
2 - Interviews
6 - Clinical rating scales
AIMS - Arthritis Impact Measurement Scales (versions; sAIMS; shortened AIMS)
CoH-QoL - City of Hope Quality of Life Tool
EORTC QLQ-C30 - European Organization for Research and Treatment of Cancer Quality of Life Questionnaires Core-30 item (versions: EORTC QLQ-C24)   
EQ-5D - EuroQoL-5 Dimensions   
FACT-G - Functional Assessment of Cancer Therapy-General
FLIC - Functional Living Interview questionnaire for Cancer
HUI - Health Utilities Index
MUMQ - Maastricht Utility Measurement Questionnaire
NHP - Nottingham Health Profile   
QLI 3.0 - Quality of Life Index 3.0
QWB - Quality of Well-Being Scale
RMDQ - Roland Morris Disability Questionnaire    
SF-12 - 12-item Short Form Health Survey [alias: RAND-12]
SF-36 - 36-item Short Form Health Survey [alias: RAND-36][alias: Medical Outcomes Study (MOS) SF-36]]    |  | also see:
SIP - Sickness Impact Profile (versions: SIP-8; SIP-68; SIP-136; SIP-SV; UKSIP)   
WHOQOL-BREF - World Health Organization Quality of Life questionnaire–Abbreviated Questionnaire (versions: WHOQOL-HIV-BREF)   
WHOQOL - World Health Organization Quality of Life Assessment (versions: WHOQOL-26)