COSMIN database

Measurement properties of rheumatoid arthritis-specific quality-of-life questionnaires: systematic review of the literature

Lee, J., Kim, S. H., Moon, S. H., and Lee, E. H.
PURPOSE: This study conducted a systematic review of the methodological quality of the psychometric evaluation process and the quality of measurement properties of rheumatoid arthritis (RA)-specific health-related quality-of-life (HRQOL) questionnaires with the purpose of obtaining the best evidence to help in the selection of the most appropriate instrument for measuring HRQOL in RA patients.

METHODS: A systematic literature search was performed to identify RA-specific HRQOL questionnaires in databases. The methodological quality of the studies was assessed using the Consensus-based Standards for the Selection of Health Measurement Instruments checklist. The quality of the measurement properties was assessed using quality criteria. The evidence regarding the measurement properties was pooled using best-evidence synthesis, with considerations of the number and methodological quality of the studies, and the consistency of their findings in terms of the quality of the measurement properties.

RESULTS: The search identified 37 studies describing 9 instruments. Best-evidence synthesis suggested that the Rheumatoid Arthritis Quality of Life (RAQoL) questionnaire had the strongest positive evidence, especially with respect to reliability, measurement error, and content validity, and moderate positive evidence with respect to hypothesis testing and responsiveness.

CONCLUSIONS: The current evidence suggests that the best-validated instrument among the RA-specific HRQOL measures is the RAQoL questionnaire in terms of both methodological quality in the process of psychometric evaluation and the quality of the measurement properties. However, there is limited evidence regarding internal consistency and structural validity of the RAQoL. Further efforts are warranted to establish the psychometric quality of this questionnaire.
Qual Life Res
1573-2649 (Electronic)
Publication year:
General health perceptions / HRQoL:
Health-related quality of life
Adults (18-65)
Children (0-18)
Seniors (65+)
Diseases of and symptoms related to the musculoskeletal system and connective tissue
PRO / non-PRO:
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
AIMS2 - Arthritis Impact Measurement Scales 2   Logozuyd
AIMS2-SF - Arthritis Impact Measurement Scales-Short Form
AIMS - Arthritis Impact Measurement Scales (Also short AIMS and shortened AIMS)
CSHQ-RA - Cedars-Sinai Health Related Quality of Life for Rheumatoid Arthritis instrument (Also: CSHQ-RA Revised - Cedars-Sinai Health Related Quality of Life for Rheumatoid Arthritis instrument Revised)
CSHQ-RA SF - Cedars-Sinai Health-Related Quality of Life for Rheumatoid Arthritis Short Form instrument
QOL-RA - Quality of Life–Rheumatoid Arthritis,
RAID - Rheumatoid Arthritis Impact of Disease
RAQoL - Rheumatoid Arthritis Quality of Life   Logozuyd
Revised CSHQ RA - Revised Cedars-Sinai Health-Related Quality of Life for Rheumatoid Arthritis instrument