COSMIN database

A review of the most common patient-reported outcomes in COPD - revisiting current knowledge and estimating future challenges

Authors:
Cazzola, M., Hanania, N. A., MacNee, W., Rudell, K., Hackford, C., and Tamimi, N.
Abstract:
Patient-reported outcome (PRO) measures that quantify disease impact have become important measures of outcome in COPD research and treatment. The objective of this literature review was to comprehensively evaluate psychometric properties of available PRO instruments and the ability of each of them to characterize pharmaceutical treatment effects from published clinical trial evidence. Identified in this study were several PRO measures, both those that have been used extensively in COPD clinical trials (St George's Respiratory Questionnaire and Chronic Respiratory Questionnaire) and new instruments whose full value is still to be determined. This suggests a great need for more information about the patient experience of treatment benefit, but this also may pose challenges to researchers, clinicians, and other important stakeholders (eg, regulatory agencies, pharmaceutical companies) who develop new treatment entities and payers (including but not limited to health technology assessment agencies such as the National Institute for Health and Care Excellence and the Canadian Agency for Drugs and Technologies in Health). The purpose of this review is to enable researchers and clinicians to gain a broad overview of PRO measures in COPD by summarizing the value and purpose of these measures and by providing sufficient detail for interested audiences to determine which instrument may be the most suitable for evaluating a particular research purpose.
DOI:
10.2147/Copd.S77368
URL:
<Go to ISI>://WOS:000352381100002
https://www.ncbi.nlm.nih.gov/pubmed/25897216
Journal:
International Journal of Chronic Obstructive Pulmonary Disease
issn:
1178-2005
Publication year:
2015
pages:
725-738
Symptom status:
Physical state
Functional status:
Physical functioning
General health perceptions / HRQoL:
Health-related quality of life
Self-rated health
Overall quality of life:
Overall quality of life
Age:
Adults (18-65)
Disease:
Diseases of and symptoms related to the respiratory system
PRO / non-PRO:
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
3 - Diaries
Instrument:
Baseline and transition index [alias: BDI-TDI - Baseline and Transition Dyspnea Indexes]
BCSS - Breathlessness, Cough and Sputum Scale
CAT - COPD Assessment Test   Logozuyd
CCQ - Clinical COPD Questionnaire    Logozuyd
CDLM - Capacity of Daily Living during the Morning questionnaire
CRDQ - Chronic Respiratory Disease Questionnaire [alias: CRQ]   Logozuyd
D-12 - Dyspnea-12
DMQ-CAT - Dyspnea Management Questionnaire Computer Adaptive Test
E-RS - Exacerbations of Chronic Pulmonary Disease Respiratory Symptoms
EXACT-PRO - Exacerbations of Chronic Pulmonary Disease Tool
GCSQ - Global Chest Symptoms Questionnaire
LCOPD - Living with chronic obstructive pulmonary disease questionnaire
McGill COPD - McGill COPD Quality of Life Questionnaire
mMRC - Modified Medical Research Council Dyspnea Scale
MRC Dyspnoea Scale - Medical Research Council Dyspnoea Scale   Logozuyd
SF-CRQ - Short Form Chronic Respiratory Disease Questionnaire
SGRQ-C - St George’s Respiratory Questionnaire for COPD
SGRQ - St. George's Respiratory Questionnaire   Logozuyd
SOBDA - Shortness of Breath with Daily Activities
VSRQ - Visual Simplified Respiratory Questionnaire