Outcome methods used in clinical studies of Chiari malformation Type I: a systematic review
Authors:
Greenberg, J. K., Milner, E., Yarbrough, C. K., Lipsey, K., Piccirillo, J. F., Smyth, M. D., Park, T. S., and Limbrick, D. D.
Abstract:
OBJECT Chiari malformation Type I (CM-I) is a common and often debilitating neurological disease. Efforts to improve treatment of CM-I are impeded by inconsistent and limited methods of evaluating clinical outcomes. To understand current approaches and lay a foundation for future research, the authors conducted a systematic review of the methods used in original published research articles to evaluate clinical outcomes in patients treated for CM-I.