COSMIN database

Self-Reported Sexual Function Measures Administered to Female Cancer Patients: A Systematic Review, 2008-2014

Jeffery, D. D., Barbera, L., Andersen, B. L., Siston, A. K., Jhingran, A., Baron, S. R., Reese, J. B., Coady, D. J., Carter, J., and Flynn, K. E.
A systematic review was conducted to identify and characterize self-reported sexual function (SF) measures administered to women with a history of cancer. Using 2009 PRISMA guidelines, we searched electronic bibliographic databases for quantitative studies published January 2008-September 2014 that used a self-reported measure of SF, or a quality of life (QOL) measure that contained at least 1 item pertaining to SF. Of 1,487 articles initially identified, 171 were retained. The studies originated in 36 different countries with 23% from US-based authors. Most studies focused on women treated for breast, gynecologic, or colorectal cancer. About 70% of the articles examined SF as the primary focus; the remaining examined QOL, menopausal symptoms, or compared treatment modalities. We identified 37 measures that assessed at least one domain of SF, eight of which were dedicated SF measures developed with cancer patients. Almost one third of the studies used EORTC QLQ modules to assess SF, and another third used the Female Sexual Function Inventory. There were few commonalities among studies, though nearly all demonstrated worse SF after cancer treatment or compared to healthy controls. QOL measures are better suited to screening while dedicated SF questionnaires provide data for more in depth assessment. This systematic review will assist oncology clinicians and researchers in their selection of measures of SF and encourage integration of this quality of life domain in patient care.
J Psychosoc Oncol
1540-7586 (Electronic)
Publication year:
Symptom status:
Physical state
Functional status:
Social functioning
General health perceptions / HRQoL:
Self-rated health
Overall quality of life:
Overall quality of life
Adults (18-65)
Diseases of and symptoms related to the genitourinary system
Neoplasms and related symptoms
PRO / non-PRO:
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
ASEX - Arizona Sexual Experiences Scale
BISF - Brief Index of Sexual Functioning (versions: BISF-W - BISF-for Women
BREAST-Q Reconstruction Module
CALGB SF - Cancer and Leukemia Group B Sexual Functioning Scale
CARES - Cancer rehabilitation evaluation system
Common Terminology Criteria Adverse Event Scale
DSFI - Derogatis Sexual Functioning Inventory
EORTC QLQ-C36 - European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire
FACIT - Functional Assessment of Chronic Illness Therapy
FACT-G - Functional Assessment of Cancer Therapy-General
FSDS - Female Sexual Distress Scale AND FSDS-Revised
FSFI - Female Sexual Function Index (and FSFI-BC - Breast Cancer)
GLQ - Gynaecologic Leiden Questionnaire
Green Climacteric Scale
GRISS - Golombok Rust Inventory of Sexual Satisfaction
IFS - Index of Female Satisfaction
MFSQ - McCoy Female Sexuality Questionnaire
MOS-SFS - Medical Outcomes Study-Sexual Functioning Scale
MSIQ - Menopausal Sexual Interest Questionnaire
MSQOL - Menopause-Specific Quality of Life Questionnaire
MSS - Menopausal Symptom Scale
PISQ-12 - Pelvic Organ Prolapse/Urinary Incontinence/Sexual Function Short Form Questionnaire
PROMIS SexFS - Patient-Reported Outcomes Measurement Information System Sexual Function and Satisfaction Measures
PSFS - Profile of Female Sexual Function
QLACS - Quality of Life in Adult Cancer Survivors
QMSP - Questionnaire of Marital Sexual Problems
QSD - Questionnaire for Screening Sexual Dysfunctions
RSS - Relationship and Sexuality
SAQ - Sexual Activity Questionnaire
SAQ - Sexual Adjustment Questionnaire
Sexual Satisfaction Measurement Tool
SFQ - Sexual Function Questionnaire
SPEQ - MSFQ short form, Personal Experiences Questionnaire
SQOL - Sexual Quality of Life (SQOL-M - Male version; SQOL-F - female version)
SSFS - Short Sexual Function Scale
SSPQ - Specific Sexual Problems Questionnaire
SSS - Swedish Sex Survey
SVQ - Sexual function-Vaginal changes Questionnaire
WHOQOL-100 - World Health Organization Quality Of Life Assessment Instrument 100 items
Women’s Health Questionnaire (WHO-Sexual function subscale)
WSFQ - Watts Sexual Function Questionnaire [alias: WSFS - Watts Sexual Functioning Scale]