COSMIN database

Systematic review of patient-reported outcome measures (PROMs) for assessing disease activity in rheumatoid arthritis

Authors:
Hendrikx, J., de Jonge, M. J., Fransen, J., Kievit, W., and van Riel, P. L.
Abstract:
Patient assessment of disease activity in rheumatoid arthritis (RA) may be useful in clinical practice, offering a patient-friendly, location independent, and a time-efficient and cost-efficient means of monitoring the disease. The objective of this study was to identify patient-reported outcome measures (PROMs) to assess disease activity in RA and to evaluate the measurement properties of these measures. Systematic literature searches were performed in the PubMed and EMBASE databases to identify articles reporting on clinimetric development or evaluation of PROM-based instruments to monitor disease activity in patients with RA. 2 reviewers independently selected articles for review and assessed their methodological quality based on the Consensus-based Standards for the selection of health Measurement Instruments (COSMIN) recommendations. A total of 424 abstracts were retrieved for review. Of these abstracts, 56 were selected for reviewing the full article and 34 articles, presenting 17 different PROMs, were finally included. Identified were: Rheumatoid Arthritis Disease Activity Index (RADAI), RADAI-5, Patient-based Disease Activity Score (PDAS) I & II, Patient-derived Disease Activity Score with 28-joint counts (Pt-DAS28), Patient-derived Simplified Disease Activity Index (Pt-SDAI), Global Arthritis Score (GAS), Patient Activity Score (PAS) I & II, Routine Assessment of Patient Index Data (RAPID) 2-5, Patient Reported Outcome-index (PRO-index) continuous (C) & majority (M), Patient Reported Outcome CLinical ARthritis Activity (PRO-CLARA). The quality of reports varied from poor to good. Typically 5 out of 10 clinimetric domains were covered in the validations of the different instruments. The quality and extent of clinimetric validation varied among PROMs of RA disease activity. The Pt-DAS28, RADAI, RADAI-5 and RAPID 3 had the strongest and most extensive validation. The measurement properties least reported and in need of more evidence were: reliability, measurement error, cross-cultural validity and interpretability of measures.
DOI:
10.1136/rmdopen-2015-000202
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013514/pdf/rmdopen-2015-000202.pdf
Journal:
RMD Open
issn:
2056-5933 (Print)
Publication year:
2016
pages:
e000202
Biological and physiological variables:
Biological and physiological variables
Symptom status:
Physical state
Age:
Adults (18-65)
Disease:
Diseases of and symptoms related to the musculoskeletal system and connective tissue
PRO / non-PRO:
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
Instrument:
GAS - Global Arthritis Scale
PAS II - Patient Activity Scale II
PAS I - Patient Activity Score I
PDAS II - Patient-based Disease Activity Score II
PDAS I - Patient-based Disease Activity Score I
PRO-CLARA - Patient Reported Outcome CLinical ARthritis Activity
PRO-Index C/M
Pt-DAS28 - Patient-derived Disease Activity Score with 28-joint counts
Pt-SDAI - Patient-derived Simplified Disease Activity Index
RADAI-5 - Rheumatoid Arthritis Disease Activity Index-5
RADAI - Rheumatoid Arthritis Disease Activity Index
RAPID 2 - Routine Assessment of Patient Index Data 2
RAPID 3 - Routine Assessment of Patient Index Data 3
RAPID 4 MDJC - Routine Assessment of Patient Index Data Medical Doctor Joint Count
RAPID 5 - Routine Assessment of Patient Index Data 5