COSMIN database

Measuring Health and Quality of Life for Women Undergoing Testing and Screening for Chlamydia: A Systematic Review

Jackson, L. J. and Roberts, T. E.
BACKGROUND: Most economic evaluations of interventions to prevent or control curable sexually transmitted infections (STIs), such as chlamydia, have focused on the longer-term health impacts avoided. However, there is a range of qualitative evidence suggesting that those who think that they might have an STI and/or undergo testing can experience impacts on their quality of life (QoL) at the testing and diagnosis stage. A systematic review was undertaken to identify and evaluate studies that have measured QoL and sexual health for women undergoing testing and screening for chlamydia.

METHODS: A systematic review was conducted, with searches of 5 electronic databases up to the end of August 2013. Data on study characteristics, methods, and results were extracted using a standard template, and a narrative synthesis was undertaken.

RESULTS: Eight studies measuring QoL and sexual health were included. The included studies measured a variety of aspects of QoL and sexual health, with a focus on psychosocial well-being. A range of validated tools were used to measure health and QoL, and "bespoke" questions were also developed. Few significant differences were found with comparator groups using generic instruments, but some impacts were found using bespoke questions.

CONCLUSIONS: Although researchers have begun to examine the relationships between QoL and sexual health, there are limitations associated with the evidence available. There is, thus, a need for further research exploring sexual health and QoL for patients undergoing testing and screening for curable STIs, with a focus on analyzing the most appropriate methodological approaches in this context.
Sex Transm Dis
Publication year:
Symptom status:
Cognitive/mental state
Emotional state
Physical state
Functional status:
Social functioning
General health perceptions / HRQoL:
Health-related quality of life
Overall quality of life:
Overall quality of life
Adults (18-65)
Diseases of and symptoms related to the genitourinary system
PRO / non-PRO:
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
BSI - Brief Symptom Inventory
FSFI - Female Sexual Function Index (and FSFI-BC - Breast Cancer)
HADS - Hospital Anxiety and Depression Scale   
Hurt, Insult, Threaten, and Scream Scale
MSQ - Minnesota Satisfaction Questionnaire
MSQ - Multidimensional Sexual Self-Concept Questionnaire
Partner Violence Screen Survey
RSES - Rosenberg Self-Esteem Scale
SCNS-P&C - Supportive Care Needs Survey–Partners and Caregivers
WHOQOL-BREF - World Health Organization Quality of Life questionnaire–Abbreviated Questionnaire [alias: WHO-QOL BREF]