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A comparative review of health-related quality-of-life measures for use in HIV/AIDS clinical trials
Authors:
Clayson, D. J., Wild, D. J., Quarterman, P., Duprat-Lomon, I., Kubin, M., and Coons, S. J.
Abstract:
With the advent of highly active antiretroviral therapy (HAART), HIV-infected patients are living longer and are concerned not only with a treatment's ability to extend their life but also with the quality of the life they are able to lead. Regulatory authorities are also paying closer attention to the use of health-related quality-of-life (HR-QOL) measures in clinical trials and to the subsequent claims that are made based on the results. This paper reviews existing HR-QOL measures reported in the HIV/AIDS literature since 1990 and identifies those most worthy of consideration for use in future clinical trials.
DOI:
Doi 10.2165/00019053-200624080-00003
URL:
<Go to ISI>://WOS:000240086500003https://www.ncbi.nlm.nih.gov/pubmed/16898846
Journal:
Pharmacoeconomics
issn:
1170-7690
Publication year:
2006
pages:
751-765
General health perceptions / HRQoL:
Health-related quality of life
Age:
Adults (18-65)
Disease:
Certain infections and parasitic diseases and related symptoms
PRO / non-PRO:
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
Instrument:
ACTG-QOL - AIDS Clinical Trial Group QOL Health Survey AIDS-HAQ - AIDS Health Assessment Questionnaire COOP/WONCA charts - COOP/WONCA Functional Healh assessment charts EORTC QLQ-C30 - European Organization for Research and Treatment of Cancer Quality of Life Questionnaires Core-30 item (versions: EORTC QLQ-C24; EORTC QLQ-C30-v1; EORTC QLQ-C30-v2; EORTC QLQ-C30v3) EQ-5D - EuroQoL-5 Dimensions (versions: EQ5D-VAS; Patient-Reported Health Score; EQ-5D-Pso - EQ-5D-Psoriasis) HI - Health Index HIV-PARSE - HIV Patient-Reported Status and Experience (versions: SF-38 HIV-PARSE; HIV-PARSE-Brief) HIV-QOL - HIV Quality of Life (versions: HIV-QOL31) HOPES - Human Immunodeficiency Virus Overview of Problems Evaluation System HUI - Health Utilities Index MOS-HIV - Medical Outcomes Study HIV Health Survey (versions: MOS-HIV-17; MOS-HIV-29) MQoL-HIV - Multidimensional Quality of Life for Persons Living with HIV/AIDS MQOL - McGill Quality of Life Questionnaire [alias: McGill QoL; MQOL-CSF - MQOL-Cardiff Short form] (versions: MQOL-7; MQOL-11) NHP - Nottingham Health Profile QLI - Quality of Life Index [alias: Ferrans and Powers Quality of Life Index] (versions: QLI-III; QLI-D - QLI-Dialysis; QLI-CV - QLI-Cancer Version; QLI-Cardiac Version; QLI-WV - QLI Wound version) Q-TWiST - Quality-Adjusted Time Without Symptoms and Toxicities QWB - Quality of Well-Being Scale (QWB-IA - QWB-interview-Administered) QWB-SA - Quality of Well Being Self-administered Scale SF-12 - 12-item Short Form Health Survey [alias: RAND-12] (versions: SF-12v2; VR-12 - Veterans SF-12; SF-12 MCS; SF-12 PCS) SF-20 - MOS short-form general health survey 20 item SF-21 - 21 items Short Form Health Survey SF-36 - 36-item Short Form Health Survey [alias: RAND-36][alias: MOS SF-36]] (versions: VSF-36 LoA - Visual Version of the SF-36 Limitations of Physical Activities domain; VR-36 - Veterans SF-36) database.cosmin.nl SF-39 - 39 items Short Form Health Survey SF-56- 56 items Short Form Health Survey SIP - Sickness Impact Profile (versions: SIP-8; SIP-68; SIP-136; SIP-SV; UKSIP; SIP/ALS-19) SWED-QOL - Swedish Health-Related QOL Survey WHOQOL-BREF - World Health Organization Quality of Life questionnaire–Abbreviated Questionnaire (versions: WHOQOL-HIV-BREF; WHOQOL-BREF dialysis) WHOQOL-HIV - WHO Quality of Life-HIV instrument
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