COSMIN database

Quality of life measures for patients on hemodialysis: a review of psychometric properties

Danquah, F. V., Wasserman, J., Meininger, J., and Bergstrom, N.
This review describes quality of life (QOL) instruments and evaluates evidence of reliability and validity as obtained from articles where QOL was assessed for patients with end stage renal disease. Articles selected for review were based on the construct of QOL measures for adult patients on hemodialysis (HD). Articles reviewed were in English and published between 1982 and 2007 as identified by searches in Medline, PubMed, Pubmed Central, SCOPUS, and CINAHL. Key words included adults, hemodialysis, ESRD, reliability, validity, QOL measures, QOL instruments, and health-related QOL instruments. Of the 146 articles meeting the inclusion criteria, 80 were reviewed. Of these, 38 articles were observational studies, and 34 QOL measures were identified. Analysis permitted sorting the instruments as generic measures (59%), patient-preference measures (15%), and disease-specific measures (26%). Studies using the most commonly used disease-specific instrument, the Kidney Disease Quality of Life Short Form (KDQOL-SF), reported minimal psychometric testing. Within the HD population, multidimensional QOL instruments that are adequately tested, reliable, and valid are needed. Since reliability and validity may vary from one group of participants to another or from one disease population to another, it is beneficial for researchers to take the time and effort to establish psychometric properties for their QOL instruments.
Nephrol Nurs J
1526-744X (Print)
Publication year:
255-69; quiz 270
Symptom status:
Cognitive/mental state
Emotional state
Physical state
Functional status:
Cognitive/mental functioning
Physical functioning
Role functioning
Social functioning
General health perceptions / HRQoL:
Health-related quality of life
Overall quality of life:
Overall quality of life
Adults (18-65)
Seniors (65+)
Diseases of and symptoms related to the genitourinary system
PRO / non-PRO:
Patient Reported Outcome
Type of measurement instrument:
1 - Questionnaires
2 - Interviews
ABS - Affect Balance Scale    | also see:
BDI - Beck Depression Inventory (versions: mBDI)   
CDI - Cognitive Depression Index
CDQOL - Chinese Dialysis Quality of Life Scale
CES-D - Centre for Epidemiologic Studies-Depression Scale (versions: CES-D-R; CES-D-8; CES-D-10; CES-D-11; CES-D-15; CES-D-20; CES-D-Children; CES-D-SF; CES-D m)   
CHEQ - CHOICE Health Experience Questionnaire
CSI - Coping Strategy Inventory
DAS - Dyadic Adjustment Scale
EQ-5D - EuroQoL-5 Dimensions   
ESRD-SI - End-stage Renal Disease Severity Index
HSS - Haemodialysis Stressor Scale
HUI-2 - Health Utilities Index Mark 2
HUI-3 - Health Utilities Index-Mark 3
IEQ - Illness Effects Questionnaire
IIRS - Illness Intrusiveness Rating Scale
JCS - Jalowiec Coping Scale
KDQ - Kidney Disease Questionnaire
KDQOL-SF - Kidney Disease Quality of Life-short form
Kidney Transplant Recipient Stressor Scale (versions: Modified Kidney Transplant Recipient stress scale)
KPS - Karnofsky Performance Scale (of: Status)
MQOL - McGill Quality of Life Questionnaire [alias: McGill QoL] (also: MQOL-CSF - MQOL-Cardiff Short form)
MSPSS - Multidimensional Scale of Perceived Social Support
NHP - Nottingham Health Profile   
PAIS - Psychosocial Adjustment to Illness Scale (versions: PAIS-SR - PAIS-Self Report)
QLI-D - Ferrans and Powers Quality of Life Index–Dialysis
Ralfrey's Specific Health Questionnaire for ESRD Patients
SF-36 - 36-item Short Form Health Survey [alias: RAND-36][alias: Medical Outcomes Study (MOS) SF-36]]    |  | also see:
SG - Standard Gamble
SUPPH - Strategies Used by People to Promote Health
SWLS - Satisfaction With Life Scale
TTO - Time Trade-Off
WHOQOL-BREF - World Health Organization Quality of Life questionnaire–Abbreviated Questionnaire (versions: WHOQOL-HIV-BREF)   
WTP - Willingness-To-Pay